Free flap reconstruction of osteoradionecrosis of the mandible: a 10-year review and defect classification

Head Neck. 2011 Jun;33(6):800-7. doi: 10.1002/hed.21537. Epub 2010 Nov 12.

Abstract

Background: The purpose of this study was to evaluate outcomes of free flap reconstruction for advanced osteoradionecrosis (ORN) defects and develop an algorithm to guide surgical planning.

Methods: All cases involving free flap reconstruction for ORN of the mandible between 1998 and 2008 were reviewed. A defect classification scheme was developed. Flap selection and outcomes were analyzed and evaluated by defect type.

Results: Seventy-five free flaps and 13 pedicle flaps were performed in 63 patients. Total flap loss was 5%. Overall surgical complication was 32%. Complication rates were higher with bone flaps than with soft tissue flaps (p = .018). A full oral diet was tolerated in 57% of patients, whereas 26% required partial tube feeding, and 16% were tube-feeding dependent.

Conclusion: Free flap reconstruction of advanced ORN defects can be safely performed in a variety of flap configurations with good outcomes. The classification scheme may assist in flap selection.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Transplantation / methods
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • Free Tissue Flaps / blood supply*
  • Graft Rejection
  • Graft Survival
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / radiotherapy
  • Head and Neck Neoplasms / surgery
  • Humans
  • Male
  • Mandibular Diseases / classification*
  • Mandibular Diseases / diagnostic imaging
  • Mandibular Diseases / surgery*
  • Middle Aged
  • Muscle, Skeletal / surgery
  • Muscle, Skeletal / transplantation
  • Osteoradionecrosis / classification*
  • Osteoradionecrosis / diagnostic imaging
  • Osteoradionecrosis / surgery*
  • Plastic Surgery Procedures / methods*
  • Quality of Life
  • Radiotherapy Dosage
  • Retrospective Studies
  • Risk Assessment
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome