Synthesis of N-arylisatins by the reaction of arynes with methyl 2-oxo-2-(arylamino)acetates

J Org Chem. 2011 Jun 17;76(12):4980-6. doi: 10.1021/jo200651b. Epub 2011 May 17.

Abstract

N-Arylisatins are efficiently prepared by the reaction of 2-oxo-2-(arylamino)acetates and arynes under mild reaction conditions.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acetates / chemistry*
  • Benzene Derivatives / chemistry
  • Isatin / chemical synthesis*
  • Methylation
  • Molecular Structure

Substances

  • Acetates
  • Benzene Derivatives
  • benzyne
  • Isatin