Response at 3 months to insulin dose decisions made at exenatide initiation in the Association of British Clinical Diabetologists (ABCD) nationwide exenatide audit

Diabetes Res Clin Pract. 2011 Aug;93(2):e87-e91. doi: 10.1016/j.diabres.2011.05.015. Epub 2011 Jun 1.

Abstract

It is uncertain what should be done with insulin dose if starting exenatide. In the ABCD nationwide exenatide audit, many patients with type 2 diabetes had worsened glycaemia when insulin was stopped. If starting exenatide, insulin should not be stopped but weaned off only if there is significant glycaemic response.

MeSH terms

  • Adult
  • Aged
  • Blood Glucose / drug effects
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Exenatide
  • Female
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Insulin / administration & dosage*
  • Male
  • Middle Aged
  • Peptides / therapeutic use*
  • Retrospective Studies
  • United Kingdom
  • Venoms / therapeutic use*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin
  • Peptides
  • Venoms
  • Exenatide