Abstract
Fecal filtrates from cows with winter dysentery were inoculated into gnotobiotic and conventional calves, and a coronavirus was isolated from calf feces. Cytopathic effects were observed on human rectal tumor cells but not bovine cell cultures. The winter dysentery isolates morphologically and antigenically resembled the Mebus strain of bovine coronavirus.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Cattle
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Cattle Diseases / microbiology*
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Coronaviridae / growth & development*
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Coronaviridae / isolation & purification
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Coronaviridae Infections / complications
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Coronaviridae Infections / veterinary*
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Cytopathogenic Effect, Viral
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Dysentery / complications
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Dysentery / veterinary*
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Germ-Free Life
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Humans
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Tumor Cells, Cultured
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Virus Cultivation