Leydig cell tumour of the ovary localised with positron emission tomography/computed tomography

Gynecol Endocrinol. 2011 Oct;27(10):837-9. doi: 10.3109/09513590.2010.521263. Epub 2011 Jun 13.

Abstract

Androgen-producing ovarian tumours can lead to assessment difficulties because of their small size. We present a case of virilising steroid cell ovarian tumour in a 41-year-old woman localised with Fluorine-18-Deoxyglucose Positron Emission Tomography/Computed Tomography ((18)FDG-PET/CT). Although the biochemical evaluation pointed to an ovarian source of androgen, diagnostic attempts to localise the source of hyperandrogenism with transvaginal ultrasound (US), and magnetic resonance imaging (MRI) of pelvis failed. Additional evaluation with (18)FDG-PET/CT showed an increased uptake in the right ovary. A laparoscopic right oophorectomy was performed and histopathology examination revealed a 1.2-cm Leydig cell tumour. The patient showed regression of clinical signs.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Leydig Cell Tumor / diagnostic imaging*
  • Leydig Cell Tumor / pathology
  • Leydig Cell Tumor / physiopathology
  • Leydig Cell Tumor / surgery
  • Multimodal Imaging
  • Ovarian Neoplasms / diagnostic imaging*
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / physiopathology
  • Ovarian Neoplasms / surgery
  • Ovariectomy
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Tumor Burden
  • Virilism / etiology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18