An H5N1 highly pathogenic avian influenza virus isolated from a local tree sparrow in Indonesia

Microbiol Immunol. 2011 Sep;55(9):666-72. doi: 10.1111/j.1348-0421.2011.00361.x.

Abstract

The isolation of an H5N1 influenza A virus from a tree sparrow (Passer montanus) captured in East Java, Indonesia in 2010 is reported here. Its hemagglutinin and neuraminidase were genetically similar to those of human isolates from 2006-2007 in Indonesia. The finding of a tree sparrow H5N1 virus that possesses genetically similar surface molecules to those of human viruses highlights the importance of monitoring resident wild birds, as well as migratory birds, for pandemic preparedness.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cluster Analysis
  • Hemagglutinin Glycoproteins, Influenza Virus / genetics
  • Indonesia
  • Influenza A Virus, H5N1 Subtype / genetics
  • Influenza A Virus, H5N1 Subtype / isolation & purification*
  • Influenza A Virus, H5N1 Subtype / pathogenicity
  • Influenza in Birds / virology*
  • Molecular Sequence Data
  • Neuraminidase / genetics
  • Phylogeny
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid
  • Sparrows / virology*
  • Viral Proteins / genetics

Substances

  • Hemagglutinin Glycoproteins, Influenza Virus
  • Viral Proteins
  • NA protein, influenza A virus
  • Neuraminidase

Associated data

  • GENBANK/AB621352
  • GENBANK/AB621353
  • GENBANK/AB621354
  • GENBANK/AB629947