Hepatitis A infection in recent international adoptees and their contacts in Minnesota, 2007-2009

Pediatrics. 2011 Aug;128(2):e333-8. doi: 10.1542/peds.2010-1840. Epub 2011 Jul 4.

Abstract

Objective: The goal of this study was to describe hepatitis A-infected adoptees and the risk of transmission to their contacts.

Methods: This was a retrospective review of adoptee-associated cases of hepatitis A and hepatitis A-infected adoptees identified in Minnesota from 2007 through 2009.

Results: From 2007 through 2009 in Minnesota, 10 cases of hepatitis A, including 1 fulminant case, were associated with international adoptees. Eight cases were direct contacts of a hepatitis A-infected adoptee, and 2 other cases secondary contacts of an adoptee. During the same period, hepatitis A infection was identified in 21 recently arrived foreign-born adoptees; all were younger than 60 months of age, and only 6 were symptomatic.

Conclusions: Clinicians should be aware that transmission of hepatitis A may occur among both direct and secondary contacts of young children recently adopted from hepatitis A-endemic areas and that infected young children may be asymptomatic. Household members and other close contacts of international adoptees should be counseled about hepatitis A prevention, including vaccination. In addition, screening for hepatitis A should be considered for recently arrived adoptees from endemic areas.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adoption*
  • Child, Preschool
  • Female
  • Global Health*
  • Hepatitis A / epidemiology*
  • Hepatitis A / prevention & control
  • Hepatitis A / transmission*
  • Humans
  • Infant
  • Male
  • Minnesota / epidemiology
  • Retrospective Studies
  • Risk Factors