Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum

ChemMedChem. 2011 Sep 5;6(9):1572-7. doi: 10.1002/cmdc.201100252. Epub 2011 Jul 5.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Antimalarials / chemical synthesis
  • Antimalarials / chemistry
  • Antimalarials / pharmacology*
  • Crystallization
  • Diterpenes / chemical synthesis
  • Diterpenes / chemistry
  • Diterpenes / pharmacology*
  • Heme / chemistry*
  • Heme / metabolism
  • Humans
  • Malaria, Falciparum / drug therapy*
  • Malaria, Falciparum / metabolism
  • Malaria, Falciparum / parasitology
  • Plasmodium falciparum / drug effects*
  • Plasmodium falciparum / growth & development
  • Plasmodium falciparum / metabolism
  • Seaweed / metabolism*

Substances

  • Antimalarials
  • Diterpenes
  • bromophycolide A
  • Heme