Abstract
Lodoxamide, a xanthine oxidase inhibitor, has antiphlogistic effects in the treatment of acute uveitis. The role of xanthine oxidase generated free radicals is discussed.
MeSH terms
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Animals
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Disease Models, Animal
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Drug Evaluation
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Endophthalmitis / drug therapy
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Endophthalmitis / metabolism
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Oxamic Acid / analogs & derivatives*
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Oxamic Acid / pharmacology
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Oxamic Acid / therapeutic use
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Rats
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Superoxides / metabolism*
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Uveitis / drug therapy*
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Uveitis / metabolism
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Xanthine Oxidase / antagonists & inhibitors*
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Xanthine Oxidase / metabolism
Substances
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Superoxides
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Xanthine Oxidase
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Oxamic Acid
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lodoxamide ethyl