Abstract
Phytochemical investigation of Caralluma adscendens var. gracilis and Caralluma pauciflora (Asclepiadaceae) whole plant extracts allowed to isolate one pregnane glycoside and two pregnanes characterized as 12β,20-O-dibenzoyl-5α,6-dihydrosarcostin β-oleandropyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-digitoxypyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-cymaropyranoside (1), 12β-O-benzoyl-3β,11α,14β,20R-pentahydroxy-pregn-5-ene (2), and 11α-O-benzoyl-3β,12β,14β,20R-pentahydroxy-pregn-5-ene (3), respectively. Their structural characterization was obtained on the basis of extensive NMR spectral studies. Three known pregnane glycosides along with lupeol and β-sitosterol were also isolated and characterized.
Copyright © 2011 Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Apocynaceae / chemistry*
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Pentacyclic Triterpenes / chemistry
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Pentacyclic Triterpenes / isolation & purification
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Plant Extracts / chemistry*
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Pregnanes / chemistry
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Pregnanes / isolation & purification*
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Sitosterols / chemistry
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Sitosterols / isolation & purification
Substances
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11alpha-O-benzoyl-3beta,12beta,14beta,20R-pentahydroxy-pregn-5-ene
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12beta,20-O-dibenzoyl-5alpha,6-dihydrosarcostin beta-oleandropyranosyl-(1-4)-beta-cymaropyranosyl-(1-4)-beta-digitoxypyranosyl-(1-4)-beta-cymaropyranosyl-(1-4)-beta-cymaropyranoside
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12beta-O-benzoyl-3beta,11alpha,14beta,20R-pentahydroxy-pregn-5-ene
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Glycosides
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Pentacyclic Triterpenes
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Plant Extracts
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Pregnanes
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Sitosterols
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gamma-sitosterol
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lupeol