Olfactory dysfunction in allergic fungal rhinosinusitis

Arch Otolaryngol Head Neck Surg. 2011 Jul;137(7):694-7. doi: 10.1001/archoto.2011.105.

Abstract

Objective: To correlate patient reports of olfactory dysfunction after surgical intervention for allergic fungal rhinosinusitis (AFRS) with endoscopic findings, psychophysical testing, and quality-of-life scores.

Design: A prospective cohort study.

Setting: A tertiary care rhinology clinic at St Paul's Hospital, Vancouver, British Columbia, Canada.

Patients: Eighty-one patients with AFRS seen at routine postoperative follow-up.

Main outcome measures: The Sniffin' Sticks test and a visual analog scale for the perceived olfactory ability of patients with AFRS were administered, along with a 36-Item Short-Form Health Survey. An endoscopic staging score was assigned for each patient.

Results: Forty men and 41 women with AFRS underwent olfactory testing; 52 of these individuals completed all parts of the assessment. The mean threshold, discrimination, and identification score was 19 (hyposmic), with a significant correlation between patients' performance on the Sniffin' Sticks test and endoscopic staging, as well as their reported olfactory ability (P < .001 for all 3 tests). The mean score for the 36-Item Short-Form Health Survey was 71, but there was a poor correlation between it and the threshold, discrimination, and identification score; visual analog scale; and endoscopic scores (P > .05 for all 3 tests).

Conclusion: All patients with AFRS should be evaluated with olfactory testing and treated according to the results.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Mycoses / complications*
  • Mycoses / microbiology
  • Mycoses / physiopathology
  • Olfaction Disorders / epidemiology
  • Olfaction Disorders / etiology*
  • Olfaction Disorders / physiopathology
  • Prospective Studies
  • Rhinitis, Allergic, Perennial / complications*
  • Rhinitis, Allergic, Perennial / microbiology
  • Rhinitis, Allergic, Perennial / physiopathology
  • Severity of Illness Index
  • Sinusitis / complications*
  • Sinusitis / microbiology
  • Sinusitis / physiopathology
  • Smell*