From struma ovarii to Hashimoto disease--an unusual diagnosis of primary hypothyroidism: case report

Gynecol Endocrinol. 2012 Jan;28(1):43-5. doi: 10.3109/09513590.2011.588750. Epub 2011 Jul 23.

Abstract

Capsule: Authors report a case of a 52-year-old woman after struma ovarii with chronic lymphocytic inflammation excision. Finally thyroxin treatment was started and patient's hypothyroidism symptoms diminished.

Case summary: Struma ovarii is a type of mature teratoma in which thyroid tissue forms the main component. In most cases struma ovarii is composed of normal thyroid tissue while lymphocytic thyroiditis in struma ovarii occurs very rarely. The authors report a case of a 52-year-old woman after ovarian tumor excision. In histopatholgical examination struma ovarii with chronic lymphocytic inflammation was diagnosed. Additional studies revealed a typical ultrasonographic picture of Hashimoto disease in the thyroid gland and an increased concentration of thyroglobulin antibodies. A final diagnosis of Hashimoto disease was confirmed. Initially, thyroid gland function was normal but 11 months after surgery, supplementation therapy with thyroxin was administered. In this case, an early diagnosis of Hashimoto disease resulted from excision of struma ovarii with chronic lymphocytic inflammation. It induced early thyroxin treatment and allowed to reduce hypothyroidism symptoms.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Female
  • Hashimoto Disease / complications
  • Hashimoto Disease / diagnosis*
  • Hashimoto Disease / pathology
  • Humans
  • Hypothyroidism / complications
  • Hypothyroidism / diagnosis*
  • Hypothyroidism / pathology
  • Middle Aged
  • Ovarian Neoplasms / complications
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / pathology
  • Struma Ovarii / complications
  • Struma Ovarii / diagnosis*
  • Struma Ovarii / pathology