The French Federation of Nursing Student (FNESI) conducted a study in nursing studies institutions from 6 administrative Regions in order to understand risk factors linked with stress or satisfaction of students. Conducted from september 2008 to june 2009, the response rate was 71.2%. Bivariate analysis were conducted on a sample selected by random of 1450 students, to determine potentials risk factors linked with poorer estimated general health and stress. Students declare more and more frequently stress or poor general health in second and third year of nursing studies. Their life habits are inadequate and do not improve when their knowledge increases: lack of sport practice, tobacco smoke, alcohol consumption, other addictive substances ... Among students who declare a too much supported rhythm of training or a poor quality of training, the majority qualify their health of bad. Practical training is considered by a quarter of first year student and 44% of second and third year students. Existence of "speech groups" and free discussion groups have a major influence on satisfaction or stress and poor general health declaration. This study demonstrated the major influence of good mentorship quality by trained nurses and that this nurse in a tutorial position has to be the same all along the training in each department. These aspects have to be improved in order to attract and retain motivated students.