Determinants of mortality of preterm babies in the university of Ilorin Teaching Hospital, Ilorin Nigeria

Niger Postgrad Med J. 2010 Dec;17(4):291-6.

Abstract

Aims and objectives: A prospective study to identify the determinants of mortality among 185 preterm babies at the University of Ilorin Teaching Hospital, Ilorin.

Subjects and methods: Data on 185 preterm babies and their mothers were collected over a nine month period in a tertiary hospital to identify the determinants of mortality among these babies.

Results: Factors identified as significant determinants of mortality were severe perinatal asphyxia (p = 0.000; OR = 71.31; 95% CI = 17.63-308.24), apnoea (p = 0.000; OR = 178.20; 95% CI = 20.64-7709.02), necrotizing entero-colitis (p = 0.001) and resuscitation duration (p = 0.003; OR = 5.33; 95% CI = 1.62-19.02).

Conclusion: The primary causes of death are severe perinatal asphyxia, respiratory distress syndrome and infection. In Nigeria, survival below 28 weeks gestation is less than 20%. The findings in this study highlight the need for prompt and effective resuscitation of these infants by a trained health worker with verifiable competence in newborn resuscitation. It also highlights the need for availability of functional facilities like ventilators and resources like surfactant.

MeSH terms

  • Adolescent
  • Adult
  • Cause of Death*
  • Female
  • Gestational Age
  • Hospitals, Teaching / statistics & numerical data*
  • Humans
  • Infant
  • Infant Mortality*
  • Infant, Newborn
  • Infant, Premature*
  • Logistic Models
  • Male
  • Maternal Age
  • Nigeria / epidemiology
  • Prospective Studies
  • Risk Factors
  • Socioeconomic Factors
  • Young Adult