Abstract
This study appreciated the efficiency of uncomplicated malaria second line treatment (P. falciparum) in an area with high level of chemoresistance. No therapeutic failure was found with sulfadoxine-pyrimethamine (Fansidar), and mefloquine-sulfadoxine-pyrimethamine (Fansimef), in contrast with a rate of 8% with quinine. The authors discuss the place of these therapeutic, in the treatment of malaria.
MeSH terms
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Adolescent
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Animals
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Antimalarials / therapeutic use*
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Child
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Child, Preschool
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Chloroquine / pharmacology
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Chloroquine / therapeutic use
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Drug Combinations / therapeutic use
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Drug Resistance
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Female
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Humans
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Infant
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Malaria / drug therapy*
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Malaria / parasitology
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Male
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Mefloquine / analogs & derivatives*
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Mefloquine / therapeutic use
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Plasmodium falciparum / drug effects*
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Pyrimethamine / therapeutic use*
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Sulfadoxine / therapeutic use*
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Sulfanilamides / therapeutic use*
Substances
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Antimalarials
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Drug Combinations
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Sulfanilamides
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fanasil, pyrimethamine drug combination
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mefloquine-sulfadoxine-pyrimethamine
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Sulfadoxine
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Chloroquine
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Mefloquine
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Pyrimethamine