[Uncomplicated malaria attack in an area with high resistance to chloroquine. 3. The use of second-choice oral drug treatment]

Bull Soc Pathol Exot. 1990;83(1):61-5.
[Article in French]

Abstract

This study appreciated the efficiency of uncomplicated malaria second line treatment (P. falciparum) in an area with high level of chemoresistance. No therapeutic failure was found with sulfadoxine-pyrimethamine (Fansidar), and mefloquine-sulfadoxine-pyrimethamine (Fansimef), in contrast with a rate of 8% with quinine. The authors discuss the place of these therapeutic, in the treatment of malaria.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Animals
  • Antimalarials / therapeutic use*
  • Child
  • Child, Preschool
  • Chloroquine / pharmacology
  • Chloroquine / therapeutic use
  • Drug Combinations / therapeutic use
  • Drug Resistance
  • Female
  • Humans
  • Infant
  • Malaria / drug therapy*
  • Malaria / parasitology
  • Male
  • Mefloquine / analogs & derivatives*
  • Mefloquine / therapeutic use
  • Plasmodium falciparum / drug effects*
  • Pyrimethamine / therapeutic use*
  • Sulfadoxine / therapeutic use*
  • Sulfanilamides / therapeutic use*

Substances

  • Antimalarials
  • Drug Combinations
  • Sulfanilamides
  • fanasil, pyrimethamine drug combination
  • mefloquine-sulfadoxine-pyrimethamine
  • Sulfadoxine
  • Chloroquine
  • Mefloquine
  • Pyrimethamine