Abstract
Stenotrophomonas maltophilia encodes proteins related to the Rax proteins of Xanthomonas oryzae, which are required for the synthesis and secretion of the Ax21 protein. Here we show that Ax21 acts as a cell-cell signal to regulate a diverse range of functions, including virulence, in this nosocomial pathogen.
Publication types
-
Research Support, Non-U.S. Gov't
-
Retracted Publication
MeSH terms
-
Bacterial Proteins / genetics
-
Bacterial Proteins / metabolism*
-
Cross Infection / microbiology*
-
Gene Expression Regulation, Bacterial
-
Humans
-
Signal Transduction*
-
Stenotrophomonas maltophilia / genetics
-
Stenotrophomonas maltophilia / metabolism*
-
Stenotrophomonas maltophilia / pathogenicity*
-
Virulence
-
Xanthomonas / genetics
-
Xanthomonas / metabolism
-
Xanthomonas / pathogenicity