The dermatologists, in their educational training, learn to observe, recognize and classify lesions in order to obtain those stereotypes that allow them to make the diagnosis. For this reason, they have not felt the need to develop means to flank examination. For some years, however, this sort of prejudice is disappearing and also dermatology has begun to make use of semiotics instrumental. Among the most tried and tested equipment in clinical practice, worth remembering the dermoscopy and digital dermoscopic analysis. The recent availability of digital cameras and phones equipped with the latest generation of optical systems capable of capturing images of pigmented lesions in epiluminescence, has further expanded the range of tools at our disposal.