Abstract
A 46,XX,r(16) "de novo" karyotype is reported in a 4 7/12-year-old girl. In spite of the mild cranio-facial dysmorphism without visceral malformations in r(16) patients, the proband's phenotype is similar to the other four previous case reports. This could support the hypothesis of a specific "r(16) syndrome".
MeSH terms
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Abnormalities, Multiple / genetics*
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Cells, Cultured
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Child, Preschool
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Chromosome Aberrations* / genetics*
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Chromosome Disorders*
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Chromosomes, Human, Pair 16 / ultrastructure*
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Female
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Humans
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Intellectual Disability / genetics
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Lymphocytes / ultrastructure
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Psychomotor Disorders / genetics
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Ring Chromosomes*
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Seizures / genetics