Genomic and antigenic characterization of Jos virus

J Gen Virol. 2012 Feb;93(Pt 2):293-298. doi: 10.1099/vir.0.035121-0. Epub 2011 Oct 12.

Abstract

Jos virus (JOSV), originally isolated in Jos, Nigeria in 1967, has remained unclassified despite cultivation in tissue culture, development of animal models of infection and implementation of seroprevalence surveys for infection. Here, we report genetic, ultrastructural and serological evidence that JOSV is an orthomyxovirus distinct from but phylogenetically related to viruses of the genus Thogotovirus.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Antigens, Viral / immunology*
  • Cluster Analysis
  • Genome, Viral*
  • Mice
  • Microscopy, Electron, Transmission
  • Molecular Sequence Data
  • Nigeria
  • Phylogeny
  • RNA, Viral / genetics
  • Sequence Analysis, DNA
  • Thogotovirus / classification
  • Thogotovirus / genetics*
  • Thogotovirus / immunology*
  • Thogotovirus / ultrastructure
  • Viral Proteins / immunology*
  • Virion / ultrastructure

Substances

  • Antigens, Viral
  • RNA, Viral
  • Viral Proteins

Associated data

  • GENBANK/HM627170
  • GENBANK/HM627171
  • GENBANK/HM627172
  • GENBANK/HM627173
  • GENBANK/HM627174
  • GENBANK/HM627175