Clinical use of allogeneic bone granulates to reconstruct maxillary and mandibular alveolar processes

Transplant Proc. 2011 Oct;43(8):3142-4. doi: 10.1016/j.transproceed.2011.08.002.

Abstract

Introduction: Lack of adequate mass of a patient's own bone is still a clinical problem in dental implantology; it precludes dental embedment. Surgical widening of an atrophied alveolar process with the use of an allogeneic bone granulate to fill the bone defect constitutes a first-line method to prepare for implant-prosthetic treatment. Transplantation of allogeneic material allows reconstruction of optimal height, thickness, and width of the alveolar process facilitating a procedure with a good long-term outcome. The study assessed outcomes following augmentation of atrophied alveolar processes before intraosseous implantation.

Materials and methods: Filling bone defects in the maxilla and mandible as an introductory measure for implant-prosthetic treatment was performed in 59 patients (24 females and 35 males of age range 22-65 years). Bone granulate was used for maxillary sinus floor elevation (n=29), augmentation of the postextraction alveoli (n=12), and filling of defects in the outer table of the compact bone formed following inflammatory conditions (n=18). The bone grafts were covered with plasma-rich fibrin (PRF) obtained from the patient's blood to accelerate the formation of synostoses and prevent epithelial penetration between the patients' own bone and the bone graft.

Results: In all of the patients normal union was observed, as confirmed by radiological images as well as intraprocedural assessment. Sufficient height and width as well as thickness of the alveolar process was obtained, which allowed embedment.

Conclusions: Allogeneic bone granulate constitutes a good material to reconstruct maxillary and mandibular alveolar processes in out-patient care.

MeSH terms

  • Adult
  • Aged
  • Alveolar Bone Loss / surgery*
  • Alveolar Process / surgery
  • Bone Transplantation / methods*
  • Dental Implantation, Endosseous / methods
  • Female
  • Humans
  • Male
  • Mandible / surgery
  • Maxilla / surgery
  • Middle Aged
  • Transplantation, Homologous
  • Young Adult