Multiple Aspergillus cerebellar abscesses in a middle-aged female: case report and literature review

Int J Med Sci. 2011;8(7):635-9. doi: 10.7150/ijms.8.635. Epub 2011 Oct 14.

Abstract

Aspergillus abscesses in the cerebellum are extremely rare, and most cases are solitary. Here, we report the first case of multiple Aspergillus cerebellar abscesses in a 46-year-old female after one mastoidectomy, two craniectomies, and extended use of antibiotics. The possible pathogenesis of this unusual event is discussed. Good outcome was achieved by treatment with a combination of neurosurgical resection and voriconazole (VRC) administration, which we suggest is a potential management plan.

Keywords: Aspergillus; Cerebellum; Neurosurgical resection; Voriconazole.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aspergillosis / diagnosis*
  • Aspergillosis / microbiology
  • Aspergillosis / surgery
  • Aspergillus / isolation & purification*
  • Brain Abscess / diagnosis*
  • Brain Abscess / drug therapy
  • Brain Abscess / microbiology
  • Brain Abscess / surgery
  • Combined Modality Therapy
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Tomography, X-Ray Computed
  • Treatment Outcome