TOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia

Br J Haematol. 2012 Apr;157(1):128-31. doi: 10.1111/j.1365-2141.2011.08908.x. Epub 2011 Nov 3.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chromosomes, Human, Pair 11 / genetics*
  • Chromosomes, Human, Pair 11 / metabolism
  • Chromosomes, Human, Pair 17 / genetics*
  • Chromosomes, Human, Pair 17 / metabolism
  • DNA Topoisomerases, Type I / genetics*
  • DNA Topoisomerases, Type I / metabolism
  • Histone-Lysine N-Methyltransferase
  • Humans
  • Leukemia, Myeloid, Acute / blood
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / pathology
  • Male
  • Middle Aged
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • Myeloid-Lymphoid Leukemia Protein / metabolism
  • Oncogene Proteins, Fusion / genetics*
  • Oncogene Proteins, Fusion / metabolism
  • Translocation, Genetic*

Substances

  • KMT2A protein, human
  • Oncogene Proteins, Fusion
  • Myeloid-Lymphoid Leukemia Protein
  • Histone-Lysine N-Methyltransferase
  • DNA Topoisomerases, Type I