Prevalence of the delta F508 deletion of the cystic fibrosis gene in Belgian patients

P Cochaux; R van Geffel; D Baran; J Poncin; G Vassart

doi:10.1007/BF02428275

Prevalence of the delta F508 deletion of the cystic fibrosis gene in Belgian patients

Hum Genet. 1990 Sep;85(4):400. doi: 10.1007/BF02428275.

Authors

P Cochaux¹, R van Geffel, D Baran, J Poncin, G Vassart

Affiliation

¹ Service de Génétique (Bat. C), Hôpital Erasme, Brussels, Belgium.

PMID: 2210745
DOI: 10.1007/BF02428275

Abstract

A sample of 107 Belgian cystic fibrosis patients has been tested for the presence of the delta F508 deletion. We have shown that 166 (78%) of the CF chromosomes presented the deletion, and that 97% of the deleted chromosomes and 50% of the non-deleted chromosomes presented the haplotype B (KM19-2/XV2c-1).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Belgium / epidemiology
Chromosome Deletion*
Cystic Fibrosis / epidemiology
Cystic Fibrosis / genetics*
Gene Frequency
Haplotypes
Humans