Drug delivery and imaging with polydiacetylene micelles

Chemistry. 2012 Jan 9;18(2):400-8. doi: 10.1002/chem.201102769. Epub 2011 Dec 2.

Abstract

This concept article summarizes our recent findings regarding photopolymerized micelles obtained from the self-assembly of diacetylene-containing amphiphiles. Their synthesis and characterization are presented as well as some biomedical applications, such as tumor imaging and drug delivery. Finally, ongoing studies and future challenges are briefly discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Drug Delivery Systems / methods*
  • Humans
  • Mice
  • Micelles*
  • Neoplasms / diagnosis*
  • Nitrilotriacetic Acid / chemistry
  • Polyacetylene Polymer
  • Polyethylene Glycols / chemistry
  • Polymerization
  • Polymers / chemistry*
  • Polyynes / chemistry*
  • Rats
  • Surface-Active Agents / chemistry*

Substances

  • Micelles
  • Polyacetylene Polymer
  • Polymers
  • Surface-Active Agents
  • Polyynes
  • polydiacetylene
  • Polyethylene Glycols
  • Nitrilotriacetic Acid