Arthroscopic treatment of hip chondral defects: autologous chondrocyte transplantation versus simple debridement--a pilot study

Arthroscopy. 2012 Mar;28(3):322-9. doi: 10.1016/j.arthro.2011.08.304. Epub 2011 Dec 3.

Abstract

Purpose: To compare the effectiveness of simple arthroscopic debridement versus arthroscopic autologous chondrocyte transplantation (ACT) for the treatment of hip chondral lesions.

Methods: We carried out a controlled retrospective study of 30 patients affected by a post-traumatic hip chondropathy of the third or fourth degree, according to the Outerbridge classification, measuring 2 cm² in area or more. Of these patients, 15 underwent arthroscopic ACT, whereas the other 15 underwent arthroscopic debridement. The 2 groups were similar in age, sex, degree, and location of the pathology. All the patients were assessed before and after the procedure with the Harris Hip Score (HHS).

Results: In both groups the mean follow-up was approximately 74 months (range, 72 to 76 months). The mean size of the defect was 2.6 cm². The patients who underwent ACT (group A) improved after the procedure compared with the group that underwent debridement alone (group B). The mean HHS preoperatively was 48.3 (95% confidence interval [CI], 45.4 to 51.2) in group A and 46 (95% CI, 42.7 to 49.3) in group B (P = .428 [no significant difference]). The final HHS was 87.4 (95% CI, 84.3 to 90.5) in group A and 56.3 (95% CI, 54.4 to 58.7) in group B (P < .001 [significant difference]).

Conclusions: This study indicates that an ACT procedure can be used in the hip for acetabular chondral defects.

Level of evidence: Level III, retrospective comparative study.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Acetabulum
  • Adult
  • Arthroscopy* / rehabilitation
  • Cartilage Diseases / etiology
  • Cartilage Diseases / rehabilitation
  • Cartilage Diseases / surgery*
  • Chondrocytes / transplantation*
  • Debridement / methods*
  • Female
  • Follow-Up Studies
  • Hip Injuries / complications*
  • Hip Joint / pathology
  • Hip Joint / surgery*
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Postoperative Complications
  • Retrospective Studies
  • Transplantation, Autologous
  • Treatment Outcome