Abstract
The Krüppel-like factor family of transcription factors plays an important role in differentiation, function, and homeostasis of many cell types. While their role in lymphocytes is still being determined, it is clear that these factors influence processes as varied as lymphocyte quiescence, trafficking, differentiation, and function. This review will present an overview of how these factors operate and coordinate with each other in lymphocyte regulation.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Animals
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B-Lymphocyte Subsets / cytology*
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B-Lymphocyte Subsets / immunology*
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B-Lymphocyte Subsets / metabolism
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Cell Differentiation / genetics
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Cell Differentiation / immunology
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Cell Movement / genetics
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Cell Movement / immunology
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Gene Targeting
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Humans
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Kruppel-Like Transcription Factors / deficiency
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Kruppel-Like Transcription Factors / metabolism
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Kruppel-Like Transcription Factors / physiology*
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Resting Phase, Cell Cycle / genetics
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Resting Phase, Cell Cycle / immunology
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T-Lymphocyte Subsets / cytology*
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T-Lymphocyte Subsets / immunology*
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T-Lymphocyte Subsets / metabolism
Substances
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Kruppel-Like Transcription Factors