Basaloid follicular hamartoma: a case report and review of the literature

Kaohsiung J Med Sci. 2012 Jan;28(1):57-60. doi: 10.1016/j.kjms.2011.06.034. Epub 2011 Dec 11.

Abstract

Basaloid follicular hamartoma (BFH) is a rare, benign, skin adnexal tumor. Several clinical patterns have been reported, but they all share the same histopathological features. BFH may be hereditary or nonhereditary and can be accompanied by systemic diseases. Microscopic examination of BFH shows branching cords and anastomosing strands of basaloid cells in a loose, fibrous stroma. The most important pathological differential diagnosis is infundibulocystic basal cell carcinoma. These two lesions must be differentiated carefully based on clinical presentation and histopathological picture, and even molecular studies may be needed. We present a report of a 78-year-old woman with a solitary, asymptomatic, slow-growing skin tumor on her left scalp. No associated systemic disorders were found. On the basis of an excisional biopsy performed on the tumor, a pathological diagnosis of sporadic BFH was made.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Carcinoma, Basal Cell / pathology*
  • Cysts / pathology
  • Female
  • Hamartoma / pathology*
  • Humans
  • Immunohistochemistry
  • Scalp / pathology
  • Skin Neoplasms / pathology*

Supplementary concepts

  • Basal cell carcinoma, infundibulocystic