Increased peanut-specific IgA levels in saliva correlate with food challenge outcomes after peanut sublingual immunotherapy

J Allergy Clin Immunol. 2012 Apr;129(4):1159-62. doi: 10.1016/j.jaci.2011.11.045. Epub 2012 Jan 10.

Abstract

Capsule Summary: Peanut-specific IgA in saliva correlates with DBPCFC outcomes following peanut SLIT, suggesting that peanut-specific salivary IgA may be a potential biomarker for SLIT used to treat peanut allergy.

Publication types

  • Letter

MeSH terms

  • Administration, Sublingual
  • Allergens / administration & dosage
  • Allergens / immunology*
  • Arachis / immunology*
  • Desensitization, Immunologic*
  • Humans
  • Immunoglobulin A, Secretory / blood
  • Immunoglobulin A, Secretory / metabolism*
  • Immunoglobulin E / blood
  • Immunoglobulin E / immunology
  • Peanut Hypersensitivity / immunology*
  • Peanut Hypersensitivity / therapy*
  • Saliva / immunology*
  • Treatment Outcome

Substances

  • Allergens
  • Immunoglobulin A, Secretory
  • Immunoglobulin E