Visible light-induced oxidative coupling reaction: easy access to Mannich-type products

Chem Commun (Camb). 2012 Feb 25;48(17):2337-9. doi: 10.1039/c2cc17130a. Epub 2012 Jan 18.

Abstract

An efficient methodology for the functionalization of sp(3) C-H bond adjacent to nitrogen has been developed utilizing visible light-induced photoredox catalysis. Through optimization of solvent and light source, the reaction can be rapidly achieved to provide the desired product under mild reaction conditions.