A cell-based backup to speed up pandemic influenza vaccine production

Trends Microbiol. 2012 Mar;20(3):103-5. doi: 10.1016/j.tim.2011.12.002. Epub 2012 Jan 16.

Abstract

Influenza vaccines are currently produced through egg-based methods, with one drawback being that this system is slow to respond to the surging global demand during an influenza pandemic. Alternative influenza vaccine production strategies, such as using a cell-based strategy, should be considered in pandemic situations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Culture Techniques*
  • Cell Line
  • Chick Embryo
  • Chlorocebus aethiops
  • Cytological Techniques*
  • Dogs
  • Humans
  • Influenza A virus / genetics
  • Influenza A virus / immunology
  • Influenza A virus / physiology*
  • Influenza Vaccines / biosynthesis*
  • Influenza Vaccines / genetics
  • Influenza Vaccines / immunology
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control*
  • Influenza, Human / virology
  • Pandemics
  • Vero Cells

Substances

  • Influenza Vaccines