Synthesis and plant growth promoting activity of polyhydroxylated ketones bearing the 5α-hydroxy-6-oxo moiety and cholestane side chain

Steroids. 2012 Apr;77(5):461-6. doi: 10.1016/j.steroids.2012.01.004. Epub 2012 Jan 17.

Abstract

Three polyhydroxylated ketones bearing the 5α-hydroxy-6-oxo moiety were obtained from cholesterol. Two of them show plant growth promoting activity in the bean's second internode bioassay. The obtained results indicate that the presence of the 5α-hydroxy-6-oxo moiety may be capable to induce plant growth promotion even the absence oxygenated functions in the side chain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cholestanes / chemistry*
  • Dose-Response Relationship, Drug
  • Fabaceae / drug effects
  • Fabaceae / growth & development*
  • Hydroxylation
  • Ketones / chemical synthesis*
  • Ketones / chemistry
  • Ketones / pharmacology
  • Models, Chemical*
  • Molecular Structure
  • Structure-Activity Relationship

Substances

  • Cholestanes
  • Ketones