Prevention of contrast-induced AKI--the ongoing saga

Usman Baber; Roxana Mehran

doi:10.1038/nrneph.2012.57

Prevention of contrast-induced AKI--the ongoing saga

Nat Rev Nephrol. 2012 Mar 13;8(5):260-1. doi: 10.1038/nrneph.2012.57.

Authors

Usman Baber¹, Roxana Mehran

Affiliation

¹ Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA.

PMID: 22410493
DOI: 10.1038/nrneph.2012.57

Abstract

Comparisons of sodium chloride and sodium bicarbonate for the prevention of contrast-induced acute kidney injury have produced inconclusive results. A new study by Klima et al. shows that sodium chloride provides greater renal protection than does sodium bicarbonate following exposure to contrast medium. However, this finding should be interpreted with caution.

MeSH terms

Acute Kidney Injury / chemically induced*
Acute Kidney Injury / prevention & control
Contrast Media / adverse effects*
Creatinine / blood
Glomerular Filtration Rate
Humans
Kidney / drug effects
Sodium Bicarbonate / pharmacology
Sodium Bicarbonate / therapeutic use
Sodium Chloride / pharmacology
Sodium Chloride / therapeutic use

Substances

Contrast Media
Sodium Chloride
Sodium Bicarbonate
Creatinine