Environmental conditions that influence toxin biosynthesis in cyanobacteria

Environ Microbiol. 2013 May;15(5):1239-53. doi: 10.1111/j.1462-2920.2012.02729.x. Epub 2012 Mar 20.

Abstract

Over the past 15 years, the genetic basis for production of many cyanobacterial bioactive compounds has been described. This knowledge has enabled investigations into the environmental factors that regulate the production of these toxins at the molecular level. Such molecular or systems level studies are also likely to reveal the physiological role of the toxin and contribute to effective water resource management. This review focuses on the environmental regulation of some of the most relevant cyanotoxins, namely the microcystins, nodularin, cylindrospermopsin, saxitoxins, anatoxins and jamaicamides.

Publication types

  • Review

MeSH terms

  • Cyanobacteria / genetics*
  • Cyanobacteria / metabolism*
  • Environment*
  • Gene Expression Regulation, Bacterial
  • Marine Toxins / biosynthesis
  • Marine Toxins / genetics
  • Microcystins / biosynthesis*
  • Microcystins / chemistry
  • Microcystins / genetics
  • Peptide Synthases / genetics

Substances

  • Marine Toxins
  • Microcystins
  • Peptide Synthases