Abstract
The integral nature of interactions between the gut microbiota and host is especially evident with respect to effects on the immune system and host defenses. Host-microbiota interactions are increasingly being revealed as complex and dynamic, with far-reaching effects on varied aspects of host health. This review focuses on adaptive and innate immune responses to the gut microbiota and the bidirectional nature of these host-microbe interactions.
MeSH terms
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Adaptive Immunity / physiology
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Animals
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Bacteria / immunology*
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Dendritic Cells / immunology
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Dendritic Cells / physiology
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Epithelial Cells / physiology
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Gastrointestinal Tract / immunology*
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Gastrointestinal Tract / microbiology*
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Humans
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Immunity, Innate / physiology
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Immunoglobulin A / immunology
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Immunoglobulin A / physiology
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Lymphoid Tissue / microbiology
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Lymphoid Tissue / physiology
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Metagenome
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Neutrophils / physiology
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T-Lymphocytes / immunology
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T-Lymphocytes / physiology