Comparison of hydroxyapatite-coated and uncoated pins for transfixation casting in horses

Am J Vet Res. 2012 May;73(5):724-34. doi: 10.2460/ajvr.73.5.724.

Abstract

Objective: To determine the extent to which a hydroxyapatite coating promotes pin stability in the third metacarpal bone during transfixation casting in horses.

Animals: 14 adult horses.

Procedures: 7 horses each were assigned to either an uncoated or hydroxyapatite-coated pin group. Three transcortical pins were placed in the third metacarpal bone of each horse and incorporated into a cast for 8 weeks. Insertion and extraction torque were measured, and torque reduction was calculated. Radiography was performed at 0, 4, and 8 weeks. Lameness evaluation was performed at 2, 4, 6, and 8 weeks. Bacteriologic culture of pins and pin holes was performed at pin removal.

Results: All horses used casts without major complication throughout the study. Insertion torque was higher in uncoated pins. There was no effect of group on extraction torque. Hydroxyapatite-coated pins had lower torque reduction. Five of 15 hydroxyapatite-coated pins maintained or increased stability, whereas all uncoated pins loosened. Pin hole radiolucency, lameness grades, and positive bacteriologic culture rates were not different between groups.

Conclusions and clinical relevance: Hydroxyapatite coating increased pin stability within the third metacarpal bone of horses during 8 weeks of transfixation casting but did not improve pin performance on clinical assessments. Clinical use of hydroxyapatite-coated transfixation pins may result in greater pin stability; however, further research is necessary to improve the consistency of pin osteointegration and elucidate whether clinical benefits will ultimately result from this approach in horses.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Nails / veterinary
  • Casts, Surgical / veterinary
  • Coated Materials, Biocompatible / therapeutic use*
  • External Fixators / veterinary
  • Fracture Fixation / veterinary
  • Fracture Healing
  • Horses / injuries
  • Horses / surgery*
  • Hydroxyapatites / therapeutic use*
  • Male
  • Metacarpal Bones / injuries
  • Metacarpal Bones / surgery*
  • Treatment Outcome

Substances

  • Coated Materials, Biocompatible
  • Hydroxyapatites