[Molecular genetics and clinical aspects of monogenic diabetes mellitus]

Vestn Ross Akad Med Nauk. 2012:(1):81-6.
[Article in Russian]

Abstract

The paper is dedicated to clinical and laboratory aspects of Diabetes Mellitus non-immune forms, such as neonatal Diabetes Mellitus, Maturity Onset Diabetes of young (MODY), DIDMOAD-syndrome, Wolframe syndrome, Alstrom syndrome and its determinating genes. The analysis of proper clinical results are present in this paper.

MeSH terms

  • Age of Onset
  • Aged
  • Diabetes Mellitus* / classification
  • Diabetes Mellitus* / drug therapy
  • Diabetes Mellitus* / epidemiology
  • Diabetes Mellitus* / genetics
  • Diabetes Mellitus* / metabolism
  • Female
  • Genetic Predisposition to Disease*
  • Genome-Wide Association Study
  • Genotyping Techniques
  • Glucokinase / genetics
  • Glucokinase / metabolism
  • HLA-DR Antigens / genetics
  • Humans
  • Hypoglycemic Agents / therapeutic use*
  • Infant, Newborn
  • Insulin Secretion
  • Insulin* / genetics
  • Insulin* / metabolism
  • Insulin* / therapeutic use
  • Insulin-Secreting Cells / drug effects
  • Insulin-Secreting Cells / metabolism
  • Male
  • Mutation
  • Pedigree
  • Transcription Factors / genetics
  • Transcription Factors / metabolism

Substances

  • HLA-DR Antigens
  • Hypoglycemic Agents
  • Insulin
  • Transcription Factors
  • Glucokinase