Role of a point-of-care protease activity diagnostic test in Canadian clinical practice: a Canadian expert consensus ©

Adv Skin Wound Care. 2012 Jun;25(6):267-75. doi: 10.1097/01.ASW.0000415344.22307.ba.

Abstract

Nonhealing wounds (stalled, healable) challenge affected individuals, wound clinicians, and society. Nonhealing may result despite local factors being corrected. The interplay between tissue degradation, increased inflammatory response, and abundant protease activity is a challenging quandary. A modified Delphi process was utilized to investigate a protease activity test and practice implications.

MeSH terms

  • Algorithms
  • Canada
  • Consensus
  • Delphi Technique
  • Diagnostic Tests, Routine / instrumentation*
  • Diagnostic Tests, Routine / methods
  • Humans
  • Inflammation / diagnosis
  • Inflammation / enzymology
  • Inflammation / pathology
  • Peptide Hydrolases / analysis*
  • Peptide Hydrolases / metabolism
  • Point-of-Care Systems*
  • Time Factors
  • Wound Healing
  • Wounds and Injuries / diagnosis*
  • Wounds and Injuries / metabolism
  • Wounds and Injuries / pathology

Substances

  • Peptide Hydrolases