Clear cell hidradenocarcinoma of the breast: a very rare breast skin tumor

Tumori. 2012 Mar-Apr;98(2):43e-45e. doi: 10.1700/1088.11947.

Abstract

Hidradenocarcinoma is an uncommon malignant intradermal tumor of sweat gland origin with a predilection for the face and extremities. It is encountered equally in males and females, usually in the second half of life. These tumors tend to be locally aggressive. In our case, the tumor was located relatively superficially but without any apparent connection to the overlying skin. The typical disease course includes local and sometimes multiple recurrences, and some patients develop regional lymph node and distant metastases. These type of tumors in the parenchyma of the breast are extremely rare. We report a case of hidradenocarcinoma in a 77-year-old woman who presented with a palpable inflammatory nodule in the right breast.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery
  • Aged
  • Antineoplastic Agents, Hormonal / administration & dosage
  • Axilla
  • Biomarkers, Tumor / analysis*
  • Breast Neoplasms / chemistry
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery
  • Diagnosis, Differential
  • Estrogen Receptor Modulators / administration & dosage
  • Female
  • Humans
  • Immunohistochemistry
  • Keratin-5 / analysis
  • Keratin-6 / analysis
  • Keratin-7 / analysis
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Mastectomy, Modified Radical* / methods
  • Necrosis
  • Rare Diseases*
  • Skin Neoplasms / chemistry
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery
  • Sweat Gland Neoplasms / chemistry
  • Sweat Gland Neoplasms / diagnosis*
  • Sweat Gland Neoplasms / drug therapy
  • Sweat Gland Neoplasms / pathology
  • Sweat Gland Neoplasms / surgery
  • Tamoxifen / administration & dosage
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Hormonal
  • Biomarkers, Tumor
  • Estrogen Receptor Modulators
  • Keratin-5
  • Keratin-6
  • Keratin-7
  • Tamoxifen