Patient related factors associated with long-term urinary continence after Burch colposuspension and pubovaginal fascial sling surgeries

J Urol. 2012 Aug;188(2):485-9. doi: 10.1016/j.juro.2012.04.010. Epub 2012 Jun 15.

Abstract

Purpose: We examined preoperative and postoperative patient related factors associated with continence status up to 7 years after surgery for stress urinary incontinence.

Materials and methods: Women randomized to Burch colposuspension or fascial sling surgery and assessed for the primary outcome of urinary continence 2 years after surgery were eligible to enroll in a prospective observational study. Survival analysis was used to investigate baseline and postoperative factors in the subsequent risk of stress urinary incontinence, defined as self-report of stress urinary incontinence symptoms, incontinence episodes on a 3-day diary or surgical re-treatment.

Results: Of the women who participated in the randomized trial 74% (482 of 655) were enrolled in the followup study. Urinary continence rates decreased during a period of 2 to 7 years postoperatively from 42% to 13% in the Burch group and from 52% to 27% in the sling group, respectively. Among the baseline factors included in the first multivariable model age (p = 0.03), prior stress urinary incontinence surgery (p = 0.02), menopausal status (0.005), urge index (0.006), assigned surgery (p = 0.01) and recruiting site (p = 0.02) were independently associated with increased risk of incontinence. In the final multivariable model including baseline and postoperative factors, Burch surgery (p = 0.01), baseline variables of prior urinary incontinence surgery (p = 0.04), menopausal status (p = 0.03) and postoperative urge index (p <0.001) were each significantly associated with a greater risk of recurrent urinary incontinence.

Conclusions: Preoperative and postoperative urgency incontinence symptoms, Burch urethropexy, prior stress urinary incontinence surgery and menopausal status were negatively associated with long-term continence rates. More effective treatment of urgency urinary incontinence in patients who undergo stress urinary incontinence surgery may improve long-term overall continence status.

Trial registration: ClinicalTrials.gov NCT00064662.

Publication types

  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Female
  • Follow-Up Studies
  • Humans
  • Menopause
  • Middle Aged
  • Postoperative Complications / physiopathology*
  • Proportional Hazards Models
  • Recurrence
  • Reoperation
  • Risk Factors
  • Suburethral Slings*
  • Survival Analysis
  • Urethra / surgery*
  • Urinary Incontinence, Stress / surgery*
  • Urinary Incontinence, Urge / physiopathology
  • Urodynamics / physiology*

Associated data

  • ClinicalTrials.gov/NCT00064662