Abstract
The medicinal treatment of spasticity includes use of oral treatments (baclofène and tizanidine), botulinum toxin, intrathecal baclofène and local application of alcohol or phenol. However, spasticity may not be uncomfortable and may even be useful. Therefore, all spastic diseases do not systematically require treatment. First-line treatments (oral treatments and botulinum toxin) can be considered depending on the local or diffuse nature of the spasticity and depending on the etiology.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.
MeSH terms
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Algorithms
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Amines / administration & dosage
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Amines / therapeutic use
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Baclofen / administration & dosage
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Baclofen / therapeutic use
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Botulinum Toxins, Type A / administration & dosage
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Botulinum Toxins, Type A / therapeutic use
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Clonidine / administration & dosage
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Clonidine / analogs & derivatives
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Clonidine / therapeutic use
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Cyclohexanecarboxylic Acids / administration & dosage
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Cyclohexanecarboxylic Acids / therapeutic use
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Dantrolene / administration & dosage
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Dantrolene / therapeutic use
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Double-Blind Method
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Drug Therapy, Combination
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Gabapentin
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Humans
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Infusion Pumps, Implantable
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Injections, Spinal
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Multiple Sclerosis / complications
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Multiple Sclerosis / drug therapy*
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Multiple Sclerosis / physiopathology
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Multiple Sclerosis / rehabilitation
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Muscle Relaxants, Central / administration & dosage
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Muscle Relaxants, Central / therapeutic use
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Muscle Spasticity / drug therapy*
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Muscle Spasticity / etiology
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Muscle Spasticity / physiopathology
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Muscle Spasticity / rehabilitation
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Nerve Block
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Neuromuscular Agents / administration & dosage
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Neuromuscular Agents / therapeutic use*
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Randomized Controlled Trials as Topic
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Spasm / drug therapy
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Spasm / etiology
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Spasm / physiopathology
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Vigabatrin / administration & dosage
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Vigabatrin / therapeutic use
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gamma-Aminobutyric Acid / administration & dosage
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gamma-Aminobutyric Acid / therapeutic use
Substances
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Amines
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Cyclohexanecarboxylic Acids
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Muscle Relaxants, Central
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Neuromuscular Agents
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gamma-Aminobutyric Acid
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tizanidine
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Gabapentin
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Botulinum Toxins, Type A
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Dantrolene
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Vigabatrin
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Baclofen
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Clonidine