Vesiculopustular dermatosis: an uncommon side-effect of liraglutide?

Femke Besemer; Arjan J Verschoor; Michaela Diamant; Roel P L M Hoogma

doi:10.1016/j.jdiacomp.2012.05.018

Vesiculopustular dermatosis: an uncommon side-effect of liraglutide?

J Diabetes Complications. 2012 Sep-Oct;26(5):458-9. doi: 10.1016/j.jdiacomp.2012.05.018. Epub 2012 Jun 23.

Authors

Femke Besemer¹, Arjan J Verschoor, Michaela Diamant, Roel P L M Hoogma

Affiliation

¹ Department of Internal Medicine, Groene Hart Hospital, Bleulandweg 10, 2800 BB Gouda Netherlands. fbesemer@gmail.com

PMID: 22727533
DOI: 10.1016/j.jdiacomp.2012.05.018

Abstract

Liraglutide is a GLP-1 receptor agonist, a novel medication for type 2 diabetes. We describe a case of pustules in a patient recently started on liraglutide. Common side effects of liraglutide are gastrointestinal disorders. Skin and tissue reactions are less well-known side effects. Liraglutide could be the cause of skin eruptions in this patient, possibly by immunogenicity.

Publication types

Case Reports

MeSH terms

Diabetes Mellitus, Type 2 / complications*
Diabetes Mellitus, Type 2 / drug therapy
Diagnosis, Differential
Drug Eruptions / diagnosis*
Drug Monitoring
Eructation / etiology
Fever / etiology
Glucagon-Like Peptide 1 / adverse effects
Glucagon-Like Peptide 1 / analogs & derivatives*
Glucagon-Like Peptide 1 / therapeutic use
Humans
Hypoglycemic Agents / adverse effects*
Hypoglycemic Agents / therapeutic use
Liraglutide
Male
Middle Aged
Skin Diseases, Vesiculobullous / chemically induced
Skin Diseases, Vesiculobullous / diagnosis*
Skin Diseases, Vesiculobullous / etiology
Thorax

Substances

Hypoglycemic Agents
Liraglutide
Glucagon-Like Peptide 1