A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins
Chemistry
.
2012 Jul 27;18(31):9485-90.
doi: 10.1002/chem.201200069.
Epub 2012 Jun 22.
Authors
Pil Seok Chae
1
,
Søren G F Rasmussen
,
Rohini R Rana
,
Kamil Gotfryd
,
Andrew C Kruse
,
Aashish Manglik
,
Kyung Ho Cho
,
Shailika Nurva
,
Ulrik Gether
,
Lan Guan
,
Claus J Loland
,
Bernadette Byrne
,
Brian K Kobilka
,
Samuel H Gellman
Affiliation
1
Department of Bionano Engineering, Hanyang University, Ansan, 426-791, Korea. pchae@hanyang.ac.kr
PMID:
22730191
PMCID:
PMC3493560
DOI:
10.1002/chem.201200069
No abstract available
Publication types
Research Support, N.I.H., Extramural
MeSH terms
Hydrophobic and Hydrophilic Interactions
Membrane Proteins / chemistry*
Models, Molecular
Molecular Structure
Saccharomyces cerevisiae / chemistry
Solubility
Substances
Membrane Proteins
Grants and funding
R21 HL087895/HL/NHLBI NIH HHS/United States
R01 GM095538/GM/NIGMS NIH HHS/United States
P01 GM075913/GM/NIGMS NIH HHS/United States
NS28471/NS/NINDS NIH HHS/United States
R01 NS028471/NS/NINDS NIH HHS/United States
R01 GM95538/GM/NIGMS NIH HHS/United States
P01 GM75913/GM/NIGMS NIH HHS/United States
R37 NS028471/NS/NINDS NIH HHS/United States