Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate

Héloïse Delavenne; Frederico Duarte Garcia; Jérôme Lacoste; Samuele Cortese; Aimé Charles-Nicolas; Nicolas Ballon

doi:10.1016/j.genhosppsych.2012.05.010

Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate

Gen Hosp Psychiatry. 2013 Jul-Aug;35(4):451.e7-9. doi: 10.1016/j.genhosppsych.2012.05.010. Epub 2012 Jun 25.

Authors

Héloïse Delavenne¹, Frederico Duarte Garcia, Jérôme Lacoste, Samuele Cortese, Aimé Charles-Nicolas, Nicolas Ballon

Affiliation

¹ Department of Psychiatry, Universidade Federal de Minas Gerais, Brazil.

PMID: 22739113
DOI: 10.1016/j.genhosppsych.2012.05.010

Abstract

Objective: The objective was to report a case of experienced psychosis during the treatment with methylphenidate (MPH) in a cocaine-dependent adult treated for attention-deficit/hyperactivity disorder (ADHD) with comorbid cocaine dependence.

Conclusion: ADHD is a frequent comorbidity in substance use disorder (SUD) patients. MPH may be effective in treating ADHD symptoms in SUD patients, thus preventing possible adverse outcomes. Cocaine-induced psychosis may be a risk factor for development of psychosis in the presence of a concurrent treatment with MPH.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Attention Deficit Disorder with Hyperactivity / drug therapy*
Attention Deficit Disorder with Hyperactivity / psychology
Central Nervous System Stimulants / adverse effects*
Cocaine-Related Disorders / psychology*
Humans
Male
Methylphenidate / adverse effects*
Psychoses, Substance-Induced / etiology*

Substances

Central Nervous System Stimulants
Methylphenidate