Measuring sleep quality after adenotonsillectomy in pediatric sleep apnea

Laryngoscope. 2012 Sep;122(9):2115-21. doi: 10.1002/lary.23356. Epub 2012 Jun 27.

Abstract

Objectives/hypothesis: The aim of this study was to demonstrate postoperative changes in sleep quality in children with obstructive sleep apnea (OSA), using both conventional sleep staging and electrocardiogram-based cardiopulmonary coupling (CPC) analysis. The hypothesis is that being electroencephalography (EEG)-independent, CPC may detect changes in sleep quality that traditional sleep architecture analysis cannot.

Study design: Retrospective outcome research.

Methods: We included 37 children (aged 6.89 ± 2.76 years, 28 male) with OSA who underwent adenotonsillectomy, and analyzed standard polysomnography and CPC parameters from a full-night study before and after adenotonsillectomy. High-frequency coupling (HFC) and low-frequency coupling (LFC) were used as indices of stable and unstable sleep, respectively.

Results: Adenotonsillectomy led to a significant change in CPC parameters (HFC, 50.3 ± 16.1% to 56.1 ± 14.7%, P = .03; LFC, 35.1 ± 14.5% to 27.3 ± 13.0%, P = .003), which was paralleled by improvements in the apnea-hypopnea (12.7 ± 13.7 to 1.0 ± 0.8, P < .001) and arousal index (20.8 ± 11.5 to 9.9 ± 3.9, P < .001). Polysomnographic sleep stage parameters other than the arousal index did not reflect postoperative resolution of OSA.

Conclusions: In pediatric OSA, postoperative improvement of sleep quality is more readily discernible by CPC analysis than EEG-based sleep staging. The CPC analysis may have potential advantages in the assessment of sleep quality in pediatric populations.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoidectomy / methods*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Electrocardiography / methods
  • Electroencephalography / methods
  • Female
  • Humans
  • Male
  • Monitoring, Physiologic / methods
  • Polysomnography / methods
  • Postoperative Care
  • Preoperative Care
  • Quality of Life
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Sleep / physiology*
  • Sleep Apnea, Obstructive / diagnosis*
  • Sleep Apnea, Obstructive / surgery*
  • Sleep Stages
  • Tonsillectomy / methods*