Clinical and histopathological features of orbital granular cell tumor: case report

Arq Bras Oftalmol. 2012 Mar-Apr;75(2):137-9. doi: 10.1590/s0004-27492012000200014.

Abstract

A 53 year-old woman presented with a slowly progressive, painless proptosis OS. Computed tomography disclosed a round, homogeneous, well-delimited lesion in the inferior-temporal orbit. The tumor was composed of round cells with eosinophilic granular cytoplasm. Some of the cells had larger eosinophilic granules surrounded by a clear halo; known as pustulo-ovoid bodies of Milian or Bangle bodies. The diagnosis of a granular cell tumor was then established and confirmed by immunohistochemistry. Granular cell tumors are uncommon benign soft tissue neoplasms that have a predilection for the head and neck region. Awareness of the typical histopathological features is crucial for the correct diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Granular Cell Tumor / diagnosis
  • Granular Cell Tumor / diagnostic imaging*
  • Granular Cell Tumor / pathology*
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Orbital Neoplasms / diagnosis
  • Orbital Neoplasms / diagnostic imaging*
  • Orbital Neoplasms / pathology*
  • Tomography, X-Ray Computed