Thrombotic complications without evidence of hemolysis in paroxysmal nocturnal hemoglobinuria: Is eculizumab indicated?

MeSH terms

• Adult
• Anemia, Aplastic / etiology
• Anemia, Aplastic / therapy
• Anticoagulants / adverse effects*
• Anticoagulants / therapeutic use
• Brain Ischemia / physiopathology
• Cerebral Hemorrhage / chemically induced*
• Cerebral Hemorrhage / etiology
• Cerebral Hemorrhage / physiopathology
• Fatal Outcome
• Hemoglobinuria, Paroxysmal / complications*
• Hemoglobinuria, Paroxysmal / drug therapy
• Hemoglobinuria, Paroxysmal / physiopathology
• Hepatitis, Autoimmune / complications
• Humans
• Immunosuppressive Agents / therapeutic use
• Male
• Mesenteric Vascular Occlusion / complications
• Mesenteric Vascular Occlusion / drug therapy*
• Nadroparin / adverse effects*
• Nadroparin / therapeutic use
• Occipital Lobe
• Paresis / etiology
• Parietal Lobe
• Transfusion Reaction
• Venous Thrombosis / complications
• Venous Thrombosis / drug therapy*