Lack of enhanced effect of a chlorine dioxide-based cleaning regimen on environmental contamination with Clostridium difficile spores

J Hosp Infect. 2012 Sep;82(1):64-7. doi: 10.1016/j.jhin.2012.06.004. Epub 2012 Jul 12.

Abstract

Spores of Clostridium difficile may play a significant role in transmission of disease within the healthcare environment and are resistant to a variety of detergents and cleaning fluids. A range of environmental cleaning agents has recently become available, many of which claim to be sporicidal. We investigated the effect of changing to a chlorine dioxide-based cleaning regimen on C. difficile environmental contamination and patient infection rates. The prevalence of environmental contamination was unaffected with a rate of 8% (9/120) before and 8% (17/212) following the change. Rates of patient infection were also unchanged during these periods.

MeSH terms

  • Chlorine Compounds / pharmacology*
  • Clostridioides difficile / drug effects
  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections / epidemiology
  • Disinfectants / pharmacology*
  • Environmental Microbiology*
  • Housekeeping, Hospital / methods*
  • Humans
  • Infection Control / methods*
  • Oxides / pharmacology*
  • Prevalence
  • Spores, Bacterial / drug effects
  • Spores, Bacterial / isolation & purification*

Substances

  • Chlorine Compounds
  • Disinfectants
  • Oxides
  • chlorine dioxide