Nanoplasmonic detection of adenosine triphosphate by aptamer regulated self-catalytic growth of single gold nanoparticles

Chem Commun (Camb). 2012 Oct 7;48(77):9574-6. doi: 10.1039/c2cc34632j.

Abstract

We present a nanoplasmonic aptasensor for adenosine triphosphate (ATP) by using single gold nanoparticles (GNPs) as probes. The specific aptamer-ATP binding induced conformational change could modulate the surface-dependent self-catalytic growth of GNPs, which enabled the detection of ATP with ultra-sensitivity and selectivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / analysis*
  • Aptamers, Nucleotide / chemistry*
  • Biosensing Techniques*
  • Catalysis
  • Gold / chemistry*
  • Metal Nanoparticles / chemistry*
  • Surface Properties

Substances

  • Aptamers, Nucleotide
  • Gold
  • Adenosine Triphosphate