First serologic evidence for the circulation of Crimean-Congo hemorrhagic fever virus in Romania

Vector Borne Zoonotic Dis. 2012 Sep;12(9):718-21. doi: 10.1089/vbz.2011.0768. Epub 2012 Aug 16.

Abstract

Serum samples from sheep in localities situated in the county of Tulcea, Northern Dobrogea, were tested with an IgG sandwich ELISA using a recombinant Crimean-Congo hemorrhagic fever virus (CCHFV) antigen. In all, 131 sera out of 471 tested (27.8%) had IgG antibodies specific to CCHFV. This is the first evidence for the circulation of CCHFV virus in Romania.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Viral / blood*
  • Antigens, Viral / immunology
  • Arachnid Vectors / virology*
  • Enzyme-Linked Immunosorbent Assay
  • Hemorrhagic Fever Virus, Crimean-Congo / immunology*
  • Hemorrhagic Fever, Crimean / epidemiology
  • Hemorrhagic Fever, Crimean / veterinary*
  • Hemorrhagic Fever, Crimean / virology
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Nucleoproteins / immunology
  • Recombinant Proteins
  • Romania / epidemiology
  • Sheep
  • Sheep Diseases / epidemiology*
  • Sheep Diseases / virology
  • Ticks / virology*

Substances

  • Antibodies, Viral
  • Antigens, Viral
  • Immunoglobulin G
  • Immunoglobulin M
  • Nucleoproteins
  • Recombinant Proteins