Was there a universal tRNA before specialized tRNAs came into existence?

Orig Life Evol Biosph. 1990;20(3-4):303-8. doi: 10.1007/BF01808112.

Abstract

It is generally true that evolving systems begin simply and become more complex in the evolutionary process. For those who try to understand the origin of a biochemical system, what is required is the development of an idea as to what simpler system preceeded the present one. Here we present an hypothesis that a universal tRNA molecule, capable of reading many codons may have preceeded the appearance of individual tRNAs. Evidence seems to suggest that this molecule may have been derived from a common ancestor of the contemporary 5S rRNAs and tRNAs.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biological Evolution*
  • Models, Biological
  • Origin of Life*
  • Protein Biosynthesis
  • RNA, Ribosomal, 5S / genetics
  • RNA, Transfer / genetics*

Substances

  • RNA, Ribosomal, 5S
  • RNA, Transfer